This multicolored image of chromatin was created using multiplexed fluorescence in situ hybridization and super-resolution microscopy. Credit: Xiaowei Zhuang lab High-resolution, 3D images of human chromosomes in single cells reveal how DNA structure might influence its function. In high school textbooks, human chromosomes are pictured as wonky Xs like two hotdogs jammed […]

Genes that give plant nucleus its shape discovered, also regulate copper tolerance. Researchers at the University of Tokyo have identified how the architecture of the cell nucleus can change gene activity in plants. This discovery reveals fundamental knowledge about genome regulation and points towards future methods for potentially manipulating the […]

Dopamine, serotonin involved in sub-second perception, cognition. In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals — dopamine and serotonin — are at work at sub-second speeds to shape how people perceive the world and take action based on their perception. The […]

Patrice Cani (UCLouvain) and Claude Knauf (INSERM) have discovered a ‘jammer’ that blocks communication between the gut and the brain, thus preventing proper regulation of sugar and causing insulin resistance in people with diabetes. They also discovered that a lipid produced by our body helps prevent this dysfunction and regulate […]

Brain cells called astrocytes appear in green, and purple represents the leakage of the blood-brain barrier. Together they show that leakage occurs around areas where astrocytes have been ablated. Now, in a study with potential impacts on a variety of neurological diseases, Fralin Biomedical Research Institute scientists have provided the […]

Study shows adding stem cells to educational intervention can significantly help kids with autism. Results of a clinical trial released today (September 9, 2020) in STEM CELLS Translational Medicine indicate that a combination of stem cell therapy and educational intervention can significantly help children with autism spectrum disorder (ASD). “Social communication, language, […]

Mice lacking CNOT3 in pancreatic beta cells have fewer insulin-producing cells, leading to diabetes. Credit: OIST A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University […]

Researchers from the Moscow Institute of Physics and Technology, Ivannikov Institute for System Programming, and the Harvard Medical School-affiliated Schepens Eye Research Institute have developed a neural network capable of recognizing retinal tissues during the process of their differentiation in a dish. Unlike humans, the algorithm achieves this without the […]

Animation When cells don’t divide into proper copies of themselves, living things fail to grow as they should. For the first time, scientists now understand how a protein called TANGLED1 can lead to accurate cell division in plants. Inside cells are structures called microtubules, which act like highways for moving […]

animation Billiard-like break shot to cell-membrane structures triggers brain’s loss of consciousness from anesthesia, scientists find. Surgery would be inconceivable without general anesthesia, so it may come as a surprise that despite its 175-year history of medical use, doctors and scientists have been unable to explain how anesthetics temporarily render […]