Process plagued by missing efficacy data and questionable evidence; Some experts argue that FDA’s standards for evidence are too low. Since the US Food and Drug Administration (FDA) established its accelerated approval pathway for drugs in 1992, nearly half (112) of the 253 drugs authorized have not been confirmed as […]

A systematic review of published research found that financial payments from the drug industry to U.S. physicians was associated with increased prescribing of the paying drug company’s drug. The association was consistent across all studies and several studies presented evidence that the association was not correlation, but causation, meaning the […]

A public health advisory issued by the US Food and Drug Administration (FDA) in 2003, followed by drug label warnings, indicated that children and adolescents taking antidepressants were at increased risk of developing suicidal thoughts and behaviors. Research has shown that these warnings reduced the diagnosis and treatment of depression […]

The leechbook. Credit: © The British Library Board (Royal 12 D xvii) To fight antibiotic resistance more antimicrobials are needed to treat bacterial biofilms, which protect an infection from antibiotics. Using the ‘Balds eyesalve’ medieval mixture containing every day natural ingredients such as garlic, researchers from the University of Warwick have found […]

New research from the University of East Anglia (UEA) recommends changes to the system which sees drug companies strike deals with competitors to stop them producing cheaper generic alternatives. These ‘pay-for-delay’ deals involve a payment from a branded drug manufacturer to a generic maker in order to delay market entry. […]